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póry prechodnej permeability, mitochondriálne

  1. Subject h.póry prechodnej permeability, mitochondriálne
    Subject h.Mitochondrial Permeability Transition Pore
    Entry termsmegakanál mitochondriálny
    mPTP (mitochondriálne póry prechodnej permeability)
    mPTP proteín
    English X referencesMitochondrial Megachannel
    Mitochondrial Permeability Transition Pore (mPTP)
    mPTP Protein
    Scope note in EnglishA multiprotein inner mitochondrial complex which opens only under certain pathological conditions (e.g., OXIDATIVE STRESS) uncoupling the membrane leading to APOPTOSIS and MITOCHONDRIAL TRANSMEMBRANE PERMEABILITY-DRIVEN NECROSIS particularly in CARDIOMYOCYTES during MYOCARDIAL REPERFUSION INJURY.
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