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aromatáza

  1. Subject h.aromatáza
    Subject h.Aromatase
    Entry termsCYP19
    cytochróm P-450(arom)
    cytochróm P450 CYP19
    CYP 19 (aromatáza) cytochrómu P450
    estrogén syntáza
    estrogén syntetáza
    English X referencesCYP19
    Cytochrome P-450 CYP19
    Cytochrome P-450(AROM)
    Scope note in EnglishAn enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.
    Links (7) - ARTICLES
    (1) - CiBaMed
    (6) - BOOKS
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