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C-peptid

  1. Subject h.C-peptid
    Subject h.C-Peptide
    Entry termsC-peptid proinzulínový
    C peptid spájajúci
    English X referencesProinsulin C-Peptide
    Scope note in EnglishThe middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.
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