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enzým štiepiaci bočný reťazec cholesterolu

  1. Subject h.enzým štiepiaci bočný reťazec cholesterolu
    Subject h.Cholesterol Side-Chain Cleavage Enzyme
    Entry termscholesteroldezmoláza
    cytochróm P-450 CYP11A1
    cytochróm P450(scc)
    CYP11A1
    cholesterol monooxygenáza (štiepiaca bočný reťazec)
    English X referencesCYP11A1
    Cholesterol Desmolase
    Cholesterol Monooxygenase (Side-Chain-Cleaving)
    Cytochrome P-450 CYP11A1
    Cytochrome P-450(scc)
    Scope note in EnglishA mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to C21 pregnenolone in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11A1 gene, catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.
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