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cesta aktivácie komplementu, alternatívna

  1. Subject h.cesta aktivácie komplementu, alternatívna
    Subject h.Complement Pathway, Alternative
    Entry termscesta properdínová
    cesta aktivácie komplementu, properdínová
    English X referencesAlternative Complement Pathway
    Properdin Pathway
    Scope note in EnglishComplement activation initiated by the interaction of microbial ANTIGENS with COMPLEMENT C3B. When COMPLEMENT FACTOR B binds to the membrane-bound C3b, COMPLEMENT FACTOR D cleaves it to form alternative C3 CONVERTASE (C3BBB) which, stabilized by COMPLEMENT FACTOR P, is able to cleave multiple COMPLEMENT C3 to form alternative C5 CONVERTASE (C3BBB3B) leading to cleavage of COMPLEMENT C5 and the assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.
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    (2) - BOOKS
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