Number of the records: 1
daktinomycín
SYS d003609 LBL 00000cx--j22000003--45-- 005 20240119200925.3 100 $a 19990101csloy0103----ba0 152 $b mesh 250 $a daktinomycín $x AA $x AD $x AE $x AG $x AI $x AN $x BI $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 66; ACTINOMYCIN was heading 1963-95 $8 eng 330 1-
$a A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015) $8 eng 450 $a Actinomycin $5 e $8 eng 450 $a Actinomycin D $5 e $8 eng 450 $a Meractinomycin $5 e $8 eng 450 $a aktinomycín $5 e $8 slo 450 $a aktinomycín D $5 e $8 slo 450 $a meraktinomycín $5 e $8 slo 550 $3 sllk_un_auth*d000900 $Y Anti-Bacterial Agents $5 P $a antibiotiká 550 $3 sllk_un_auth*d000903 $Y Antibiotics, Antineoplastic $5 P $a antibiotiká protinádorové 550 $3 sllk_un_auth*d019384 $Y Nucleic Acid Synthesis Inhibitors $5 P $a inhibítory syntézy nukleových kyselín 550 $3 sllk_un_auth*d011500 $Y Protein Synthesis Inhibitors $5 P $a inhibítory proteosyntézy 686 $a D03.633.300.200 686 $a D04.345.566.252 686 $a D12.644.641.252 750 $a Dactinomycin $8 eng 801 -0
$a US $b DNLM $c 19990101 801 -2
$a SK $b BA006 $c 20021127 980 $x M
Number of the records: 1