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dianhydrogalaktitol

  1. Subject h.dianhydrogalaktitol
    Subject h.Dianhydrogalactitol
    Entry termsdianhydrodulcitol
    diepoxydulcitol
    diepoxygalaktitol
    English X referencesDianhydrodulcitol
    Diepoxydulcitol
    Diepoxygalactitol
    Scope note in EnglishOne of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity.
    Pharmacology effect antineoplastiká alkylačné
    Pharmacology effect Antineoplastic Agents, Alkylating
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Number of the records: 1  

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