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poškodenie DNA

  1. Subject h.poškodenie DNA
    Subject h.DNA Damage
    Entry termsstres genotoxický
    DNA poškodenie
    lézia DNA
    lézie DNA
    DNA lézia
    DNA lézie
    English X referencesDNA Injury
    DNA Lesion
    DNA Lesions
    Genotoxic Stress
    Stress, Genotoxic
    Scope note in EnglishInjuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.
    See also reference (FX) in Slovak mutácia
    See also reference (FX) in English Mutation
    Links (80) - ARTICLES
    (5) - MeSH descriptor
    (16) - CiBaMed
    (12) - BOOKS
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Number of the records: 1  

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