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globozidy

  1. Subject h.globozidy
    Subject h.Globosides
    English X referencesCytolipins
    Lacto-N-neotetraosylceramide
    Lacto-N-tetraosylceramide
    Scope note in EnglishGlycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.
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