nezidioblasty bunky ostrovčekové pankreas endokrinný ostrovčeky pankreatické
English X references
Islands of Langerhans Islet Cells Nesidioblasts Pancreas, Endocrine Pancreatic Islets
Scope note in English
Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
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