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neuritída autoimunitná experimentálna
Subject h. neuritída autoimunitná experimentálna Subject h. Neuritis, Autoimmune, Experimental Entry terms neuritída experimentálna alergická
neuritída experimentálna autoimunitnáEnglish X references Allergic Neuritis, Experimental
Autoimmune Neuritis, Experimental
Neuritis, Experimental AllergicScope note in English An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52) 
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