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syndróm neuroleptický malígny

  1. Subject h.syndróm neuroleptický malígny
    Subject h.Neuroleptic Malignant Syndrome
    Entry termsneuroleptikami indukovaný neuroleptický malígny syndróm
    neuroleptikami spôsobený neuroleptický malígny syndróm
    neuroleptikami vyvolaný neuroleptický malígny syndróm
    syndróm neurolepticko-malígny, indukovaný neuroleptikami
    syndróm neurolepticko-malígny, spôsobený neuroleptikami
    syndróm neurolepticko-malígny, vyvolaný neuroleptikami
    English X referencesNeuroleptic-Induced Neuroleptic Malignant Syndrome
    Neuroleptic-Malignant Syndrome, Neuroleptic Induced
    Scope note in EnglishA potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
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