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fenytoín

  1. Subject h.fenytoín
    Subject h.Phenytoin
    Entry terms5,5-difenylhydantoín
    5,5-difenylimidazolidín-2,4-dión
    Antisacer
    Difenin
    Dihydan
    Dilantin
    difenylhydantoín
    Epamin
    Epanutin
    Fenitoin
    Hydantol
    Phenhydan
    fynetoín sodný
    difenylhydantoinát sodný
    English X referencesDiphenylhydantoin
    Fenitoin
    Phenhydan
    Scope note in EnglishAn anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.
    Pharmacology effect antikonvulzíva
    induktory cytochrómu P-450 CYP1A2
    blokátory sodíkových kanálov riadených napätím
    Pharmacology effect Anticonvulsants
    Cytochrome P-450 CYP1A2 Inducers
    Voltage-Gated Sodium Channel Blockers
    Links (23) - ARTICLES
    (2) - CiBaMed
    (5) - BOOKS
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Number of the records: 1  

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