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chinidín

  1. Subject h.chinidín
    Subject h.Quinidine
    Scope note in EnglishAn optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
    Pharmacology effect antagonisty alfa-adrenergických receptorov
    antiarytmiká
    antimalariká
    inhibítory cytochrómu P-450 CYP2D6
    inhibítory enzýmov
    antagonisty muskarínové
    blokátory sodíkových kanálov riadených napätím
    Pharmacology effect Adrenergic alpha-Antagonists
    Anti-Arrhythmia Agents
    Antimalarials
    Cytochrome P-450 CYP2D6 Inhibitors
    Enzyme Inhibitors
    Muscarinic Antagonists
    Voltage-Gated Sodium Channel Blockers
    Links (1) - ARTICLES
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Number of the records: 1  

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