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steroid-17-alfa-hydroxyláza

  1. Subject h.steroid-17-alfa-hydroxyláza
    Subject h.Steroid 17-alpha-Hydroxylase
    Entry termssteroid-17-alfa-monooxygenáza
    steroid-17-hydroxyláza
    cytochróm P450 (17-alfa)
    steroid-17-monooxygenáza
    CYP17
    P-450(c17)
    17-alfa-hydroxyláza
    17 alfa-hydroxyprogesterón aldoláza
    17,20-lyáza
    17,20-dezmoláza
    English X references17 alpha-Hydroxylase
    17,20-Lyase
    CYP17
    Cytochrome P-450(17 alpha)
    P450(c17)
    Steroid 17 alpha-Monooxygenase
    Steroid 17-Hydroxylase
    Steroid 17-Monooxygenase
    Scope note in EnglishA microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation.
    See also reference (FX) in Slovak hyperplázia adrenálna vrodená
    See also reference (FX) in English Adrenal Hyperplasia, Congenital
    Links (3) - ARTICLES
    (1) - MeSH descriptor
    (2) - CiBaMed
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