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faktor XIIa

  1. Subject h.faktor XIIa
    Subject h.Factor XIIa
    Entry termsfaktor koagulačný XIIa
    faktor XII, aktivovaný
    English X referencesCoagulation Factor XIIa
    Factor XII, Activated
    Scope note in EnglishActivated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation, kallikrein (with cofactor HIGH MOLECULAR WEIGHT KININOGEN) cleaves factor XII to XIIa. Factor XIIa is then further cleaved by kallikrein, plasmin, and trypsin to yield smaller factor XII fragments (Hageman-Factor fragments). These fragments increase the activity of prekallikrein to kallikrein but decrease the procoagulant activity of factor XII.
    See also reference (FX) in Slovak koagulanciá
    See also reference (FX) in English Coagulants
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