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faktor rastový transformujúci, beta

  1. Subject h.faktor rastový transformujúci, beta
    Subject h.Transforming Growth Factor beta
    Entry termsfaktor rastový transformačný, beta
    faktor transformačný rastový pochádzajúci z kosti
    faktor transformujúci rastový odvodený od kosti
    faktor supresorový T-bunkový pochádzajúci z glioblastómu
    faktor supresorový T-bunkový odvodený od glioblastómu
    faktor transformujúci rastový trombocytový
    TGF-beta
    English X referencesBone-Derived Transforming Growth Factor
    Platelet Transforming Growth Factor
    TGF-beta
    Scope note in EnglishA factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
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