These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences.
Pharmacology effect
látky rastové
Pharmacology effect
Growth Substances
See also reference (FX) in Slovak
faktor A, rastový endotelový vaskulárny
See also reference (FX) in English
Vascular Endothelial Growth Factor A
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openseadragon
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