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choroba motorických neurónov

  1. Subject h.choroba motorických neurónov
    Subject h.Motor Neuron Disease
    Entry termschoroba predných rohov miechových
    choroba motorických neurónov, familiárna
    skleróza laterálna
    choroba dolných motorických neurónov
    choroba horných motorických neurónov
    English X referencesAnterior Horn Cell Disease
    Familial Motor Neuron Disease
    Lateral Sclerosis
    Motor Neuron Disease, Lower
    Motor Neuron Disease, Upper
    Scope note in EnglishDiseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
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