polyendokrinopatia-kandidiáza-ektodermálna dystrofia, autoimunitná polyendokrinopatia-kandidóza-ektodermová dystrofia, autoimunitná syndróm autoimunitný polyendokrinný, typ 2 syndróm autoimunitnej polyendokrinopatie, typ 1 syndróm polyglandulárny autoimunitný, typ I syndróm polyglandulárny autoimunitný typu I syndróm polyglandulárny autoimunitný, typ II syndróm polyglandulárny autoimunitný typu II diabetes mellitus, Addisonova choroba, myxedém syndróm viacpočetnej endokrinnej deficiencie, typ 2 syndróm polyglandulárnej deficiencie, typ 2 Schmidtov syndróm
English X references
Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy Autoimmune Syndrome Type I, Polyglandular Autoimmune Syndrome Type II, Polyglandular Polyglandular Type I Autoimmune Syndrome Polyglandular Type II Autoimmune Syndrome Schmidt's Syndrome
Scope note in English
Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
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