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prepínanie imunoglobulínových tried

  1. Subject h.prepínanie imunoglobulínových tried
    Subject h.Immunoglobulin Class Switching
    Entry termsprepínanie tried
    prepínanie Ig tried
    prepínanie izotypov
    English X referencesClass Switching
    Ig Class Switching
    Isotype Switching
    Scope note in EnglishGene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.
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