Number of the records: 1
myši knokautované
SYS d018345 LBL 00000nx--j22000003--45-- 005 20240119201501.4 100 $a 19930603csloy0103----ba0 152 $b mesh 250 $a myši knokautované $x AB $x AH $x BL $x CF $x CL $x EM $x GD $x GE $x IM $x IN $x ME $x MI $x PH $x PS $x PX $x SU $x UR $x VI $8 slo 300 1-
$a 94 $8 eng 300 1-
$a Mice (1992-1993) $8 eng 330 1-
$a Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes. $8 eng 450 $a Knockout Mice $5 e $8 eng 450 $a myši knockout $5 e $8 slo 550 $3 sllk_un_auth*d005818 $Y Genetic Engineering $5 B $a inžinierstvo genetické 550 $3 sllk_un_auth*d055786 $Y Gene Knockout Techniques $5 F $a techniky inaktivácie génu 550 $3 sllk_un_auth*d055786 $Y Gene Knockout Techniques $5 B $a techniky inaktivácie génu 686 $a B01.050.050.136.500.500 686 $a B01.050.150.900.649.313.992.635.505.500.550.455 686 $a B01.050.150.900.649.313.992.635.505.500.800.500 750 $a Mice, Knockout $8 eng 801 -0
$a US $b DNLM $c 19930603 801 -2
$a SK $b BA006 $c 19990907 820 $a NIM no qualif when exper animal; do not forget also to check MICE $8 eng 980 $x M
Number of the records: 1