veľkorodina receptorov pre faktor nekrotizujúci nádory, člen 5 superrodina receptorov pre faktor nekrotizujúci nádory, člen 5 CD40 antigén CDw40 antigén TNFRSF5 receptor
English X references
Antigens, CD40 Tumor Necrosis Factor Receptor Superfamily, Member 5
Scope note in English
Members of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
See also reference (FX) in Slovak
ligand CD40
See also reference (FX) in English
CD40 Ligand
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(1) - MeSH descriptor
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openseadragon
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