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komplex trombocytových glykoproteínov GPIIb-IIIa

  1. Subject h.komplex trombocytových glykoproteínov GPIIb-IIIa
    Subject h.Platelet Glycoprotein GPIIb-IIIa Complex
    Entry termsreceptory GPIIb-IIIa
    integrín alfaIIbbeta3
    komplex trombocytových glykoproteínov GPIIb/IIIa
    glykoproteín doštičkový IIb/IIIa
    English X referencesGPIIb-IIIa Receptors
    Integrin alphaIIbbeta3
    Scope note in EnglishPlatelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
    See also reference (FX) in Slovak trombasténia
    See also reference (FX) in English Thrombasthenia
    Links (23) - ARTICLES
    (3) - MeSH descriptor
    (7) - CiBaMed
    (21) - BOOKS
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