An increased number of contiguous trinucleotide repeats in the DNA sequence from one generation to the next. The presence of these regions is associated with diseases such as FRAGILE X SYNDROME and MYOTONIC DYSTROPHY. Some CHROMOSOME FRAGILE SITES are composed of sequences where trinucleotide repeat expansion occurs.
See also reference (FX) in Slovak
anticipácia genetická miesta chromozómov fragilné fragilita chromozómov syndróm fragilného chromozómu X dystrofia myotonická
