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kalcineurín

Subject h.	kalcineurín
Subject h.	Calcineurin
Entry terms	kalcineurín A kalcineurín B proteínfosfatáza-2B fosfatáza proteínová 2B
English X references	Calcineurin A Calcineurin B Protein Phosphatase-2B
Scope note in English	A CALCIUM and CALMODULIN-dependent serine/threonine protein phosphatase that is composed of the calcineurin A catalytic subunit and the calcineurin B regulatory subunit. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including HISTONES; MYOSIN LIGHT CHAIN; and the regulatory subunits of CAMP-DEPENDENT PROTEIN KINASES. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes.
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