A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase A by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of TIMP-2 has been shown to inhibit invasive and metastatic activity of tumor cells and decrease tumor growth in vivo.
Pharmacology effect
inhibítory matrixových metaloproteináz
Pharmacology effect
Matrix Metalloproteinase Inhibitors
Links
(4) - ARTICLES
(1) - CiBaMed
subject heading
openseadragon
Number of the records: 1
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