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eIF-2-kináza

  1. Subject h.eIF-2-kináza
    Subject h.eIF-2 Kinase
    Entry termsp68 kináza
    proteínkináza PKR
    proteínkináza aktivovaná RNA
    proteínkináza závislá od RNA
    proteínkináza RNA-dependentná
    English X referencesProtein Kinase PKR
    Protein Kinase, RNA Activated
    RNA-Dependent Protein Kinase
    p68 Kinase
    Scope note in EnglishA dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, the kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the inhibition of protein synthesis.
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