Extracellular Signal-Regulated Kinase 2 MAP Kinase 2 Mitogen-Activated Protein Kinase 2 p42 MAP Kinase p42 MAPK p42(Mitogen-Activated Protein Kinase)
Scope note in English
A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms.
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