ATP-Dependent Translocase ABCB1 MDR1 Protein MDR1B Protein Multidrug Resistance Protein 1 P-Glycoprotein P-Glycoprotein 1
Scope note in English
A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).
See also reference (FX) in Slovak
rezistencia lieková mnohopočetná
See also reference (FX) in English
Drug Resistance, Multiple
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