Number of the records: 1  

myasthenia gravis, autoimunitná experimentálna

  1. Subject h.myasthenia gravis, autoimunitná experimentálna
    Subject h.Myasthenia Gravis, Autoimmune, Experimental
    Entry termsmyasténia gravis, autoimunitná experimentálna, pasívny prenos
    English X referencesMyasthenia Gravis, Experimental Autoimmune
    Passive Transfer Experimental Autoimmune Myasthenia Gravis
    Scope note in EnglishAny autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)
    subject heading

    subject heading

Number of the records: 1  

  This site uses cookies to make them easier to browse. Learn more about how we use cookies.