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receptor trkA

  1. Subject h.receptor trkA
    Subject h.Receptor, trkA
    Entry termsgp140(c-TRK)
    proteín protoonkogénový trk
    NTRK1 receptor
    receptor neurotrofickej tyrozínkinázy, typ 1
    receptor neurotrofnej tyrozínkinázy, typ 1
    English X referencesNTRK1 Receptor
    Proto-Oncogene Protein trk
    Receptor, Neurotrophic Tyrosine Kinase Type 1
    gp140(c-TRK)
    trk Proto-Oncogene Protein
    trkA Receptor
    Scope note in EnglishA protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with CONGENITAL INSENSITIVITY TO PAIN WITH ANHIDROSIS, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis.
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