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BRCA2 proteín

  1. Subject h.BRCA2 proteín
    Subject h.BRCA2 Protein
    Entry termsBRCA2-proteín
    BRCA-2-proteín
    produkt génový 2, nádorov prsníka
    proteín Fanconiho anémie komplementačnej skupiny D1
    English X referencesBreast Cancer 2 Gene Product
    Fanconi Anemia Complementation Group D1 Protein
    Scope note in EnglishA large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)
    See also reference (FX) in Slovak syndróm dedičnej rakoviny prsníka a vaječníkov
    See also reference (FX) in English Hereditary Breast and Ovarian Cancer Syndrome
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    (2) - MeSH descriptor
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