Number of the records: 1

proteíny spojené s mnohopočetnou liekovou rezistenciou

Subject h.	proteíny spojené s mnohopočetnou liekovou rezistenciou
Subject h.	Multidrug Resistance-Associated Proteins
Entry terms	proteíny spojené s viacnásobnou liekovou rezistenciou proteín spojený s multiliekovou rezistenciou proteín spojený s liekovou multirezistenciou proteíny asociované s viacnásobnou liekovou rezistenciou proteín asociovaný s multiliekovou rezistenciou proteín asociovaný s liekovou multirezistenciou proteíny spojené s mnohonásobnou liekovou rezistenciou proteíny asociované s mnohonásobnou liekovou rezistenciou
English X references	Multidrug Resistance-Associated Protein
Scope note in English	A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion transporters, a subset of proteins in this family have also been shown to convey drug resistance to neutral organic drugs. Their cellular function may have clinical significance for CHEMOTHERAPY in that they transport a variety of ANTINEOPLASTIC AGENTS. Overexpression of proteins in this class by NEOPLASMS is considered a possible mechanism in the development of multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although similar in function to P-GLYCOPROTEINS, the proteins in this class share little sequence homology to the ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 family of proteins.
See also reference (FX) in Slovak	ATP-viažuci kazetový transportér, podrodina B rezistencia lieková mnohopočetná
See also reference (FX) in English	ATP Binding Cassette Transporter, Subfamily B Drug Resistance, Multiple
Links	(10) - ARTICLES
	(2) - MeSH descriptor
	(2) - CiBaMed

subject heading

Number of the records: 1