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receptory aktivínové

  1. Subject h.receptory aktivínové
    Subject h.Activin Receptors
    Entry termsreceptory pre aktivín
    kinázy podobné aktivínovým receptorom
    kinázy podobné receptorom aktivínu
    English X referencesActivin Receptor-Like Kinases
    Scope note in EnglishReceptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS, TRANSFORMING GROWTH FACTOR BETA), ALK's consist of two different but related protein kinases, Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS, TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS, TYPE I ) with subsequent activation of the type I kinase activity.
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