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proteín FUS viažuci sa na RNA

  1. Subject h.proteín FUS viažuci sa na RNA
    Subject h.RNA-Binding Protein FUS
    Entry termsFUS proteín viažuci sa na RNA
    English X referencesFUS RNA-Binding Protein
    Scope note in EnglishA multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.
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