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sirtuíny

Subject h.	sirtuíny
Subject h.	Sirtuins
Entry terms	SIRT SIRTs proteíny podobné Sir2 proteínom Sir2-podobné proteíny sirtuín
English X references	SIRT Sir2-like Proteins Sirtuin
Scope note in English	A homologous family of regulatory enzymes that are structurally related to the protein silent mating type information regulator 2 (Sir2) found in Saccharomyces cerevisiae. Sirtuins contain a central catalytic core region which binds NAD. Several of the sirtuins utilize NAD to deacetylate proteins such as HISTONES and are categorized as GROUP III HISTONE DEACETYLASES. Several other sirtuin members utilize NAD to transfer ADP-RIBOSE to proteins and are categorized as MONO ADP-RIBOSE TRANSFERASES, while a third group of sirtuins appears to have both deacetylase and ADP ribose transferase activities.
See also reference (FX) in Slovak	proteíny regulačné, pre tichú informáciu, Saccharomyces cerevisiae
See also reference (FX) in English	Silent Information Regulator Proteins, Saccharomyces cerevisiae
Links	(7) - ARTICLES
	(1) - MeSH descriptor
	(4) - CiBaMed

subject heading

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