receptor 5-HT1B pre serotonín receptor pre sérotonín, 5-HT1B receptor serotonínový 1B receptor 1B pre serotonín 5-HT(1B) receptor 5-HT(1Dbeta) receptor 5-HT1B receptor 5-hydroxytryptamín 1B receptory receptor serotonínový, typ 1Dbeta receptory serotonínové 1D-beta
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Serotonin 1B Receptor
Scope note in English
A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.
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