receptor pre serotonín, 5-HT1D receptor 5-HT1D pre sérotonín receptor serotonínový 1D receptor 1D pre serotonín 5-HT (1D) receptor 5-HT 1Dalfa receptor 5-HT1Dalfa receptor 5-hydroxytryptamín 1D receptor receptor serotonínový 1D-alfa
English X references
Serotonin 1D Receptor
Scope note in English
A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.
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