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receptor PAR-2

  1. Subject h.receptor PAR-2
    Subject h.Receptor, PAR-2
    Entry termsproteinázou-aktivovaný receptor 2
    receptor 2 aktivovaný proteinázou
    English X referencesPAR-2 Receptor
    Proteinase Activated Receptor 2
    Scope note in EnglishA G-protein-coupled, proteinase-activated receptor that is expressed in a variety of tissues including ENDOTHELIUM; LEUKOCYTES; and the GASTROINTESTINAL TRACT. The receptor is activated by TRYPSIN, which cleaves off the N-terminal peptide from the receptor. The new N-terminal peptide is a cryptic ligand for the receptor. The uncleaved receptor can also be activated by the N-terminal peptide present on the activated THROMBIN RECEPTOR and by small synthetic peptides that contain the unmasked N-terminal sequence.
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