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faktory transkripčné NFATC

Subject h.	faktory transkripčné NFATC
Subject h.	NFATC Transcription Factors
Entry terms	faktor transkripčný NFAT 1 faktor transkripčný NFAT 2 faktor transkripčný NFAT 3 faktor transkripčný NFAT 4 faktor transkripčný NFAT 5 faktory nukleálne, aktivovaných T-buniek faktory nukleárne, aktivovaných T-buniek faktory aktivovaných T-buniek, nukleárny
English X references	NFAT Transcription Factor 1 NFAT Transcription Factor 2 NFAT Transcription Factor 3 NFAT Transcription Factor 4 NFAT Transcription Factor 5 Nuclear Factors of Activated T-Cells
Scope note in English	A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.
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