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proteín adaptorový Grb2

  1. Subject h.proteín adaptorový Grb2
    Subject h.GRB2 Adaptor Protein
    Entry termsproteín 2 viažuci sa na receptor rastového faktora
    English X referencesGrowth Factor Receptor-Bound Protein-2
    Scope note in EnglishA signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS).
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