RecQ rodina DNA helikáza RecQ helikáza DNA helikáza Q1, ATP-dependentná DNA helikáza Q4, ATP-dependentná DNA helikáza Q5, ATP-dependentná DNA helikáza Q1 DNA helikáza RecQL DNA helikáza RecQL4 DNA helikáza podobná RecQL , typ 2 DNA-dependentná ATPáza Q1 RECQL1 helikáza RTS helikáza RecQ rodina DNA helikáz RecQ helikáza RecQ proteín
English X references
RecQ Family of DNA Helicase RecQ Helicase
Scope note in English
A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.