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proteín tyrozín fosfatáza nereceptorová, typ 22
Subject h. proteín tyrozín fosfatáza nereceptorová, typ 22 Subject h. Protein Tyrosine Phosphatase, Non-Receptor Type 22 Entry terms proteíntyrozínfosfatáza nereceptorová, typ 22
fosfatáza lymfoidná
Lyp1 PTPáza
Lyp2 PTPáza
PTPN-22 proteín
PTPáza Lyp
proteín-tyrozín fosfatáza Lyp
tyrozín proteín fosfatáza, nereceptorový typ 22Scope note in English A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES. 
subject heading
Number of the records: 1