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faktor transkripčný 4

  1. Record numberd000073940
    Date06.06.2025
    TypeM - MESH
    Topical termfaktor transkripčný 4
    Other termSlovak (Pseudonym) TCF-4 proteín
    Slovak (Pseudonym) TCF4 transkripčný faktor
    UDCD12.776.260.108.092.937D12.776.930.125.500.937
    NoteA basic helix-loop-helix leucine zipper transcription factor that functions in neuronal CELL DIFFERENTIATION. It dimerizes with other bHLH transcription factors and activates transcription through binding to E-BOX ELEMENTS containing 5'-ACANNTGT-3' or 5'-CCANNTGG-3' sequences. Mutations in the TCF-4 gene are associated with Pitt-Hopkins Syndrome, a severe developmental disorder.
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