Number of the records: 1  

etopozid

  1. Record numberd005047
    Date06.06.2025
    TypeM - MESH
    Topical termetopozid
    Other termEnglish (Pseudonym) Demethyl Epipodophyllotoxin Ethylidine Glucoside
    Slovak (Pseudonym) Etoposide
    Slovak (Pseudonym) demetylepipodofylotoxínetylidínglukozid
    See also(Skutočné meno) antineoplastiká fytogénne
    (Skutočné meno) inhibítory topoizomerázy II
    UDCD02.455.426.559.847.638.960.675.250D04.615.638.960.675.250D09.408.348.275
    NoteA semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
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Number of the records: 1  

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