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tetanotoxín

  1. Record numberd013744
    Date06.06.2025
    TypeM
    Topical termtetanotoxín
    Other termEnglish (Pseudonym) Clostridial Neurotoxin
    English (Pseudonym) Clostridium tetani Toxin
    Slovak (Pseudonym) toxín Clostridium tetani
    Slovak (Pseudonym) neurotoxín klostrídiový
    See also(Later heading) Clostridium tetani
    (Skutočné meno) neurotoxíny
    (Skutočné meno) antitoxín tetanický
    UDCD12.776.097.872D23.946.123.893
    NoteProtein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity to BOTULINUM TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. Tetanolysin is the hemolytic and tetanospasmin is the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal CONVULSIONS.
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Number of the records: 1  

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