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tetrahydrofolátdehydrogenáza
Record number d013762 Date 06.06.2025 Type M - MESH Topical term tetrahydrofolátdehydrogenáza Other term English (Pseudonym) Dihydrofolate Dehydrogenase
English (Pseudonym) Dihydrofolate Reductase
English (Pseudonym) Folic Acid Reductase
Slovak (Pseudonym) dihydrofolátdehydrogenáza
Slovak (Pseudonym) dihydrofolátreduktáza
Slovak (Pseudonym) reduktáza kyseliny listovej
UDC D08.811.682.662.825 Note An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. (Dorland, 27th ed) EC 1.5.1.3. 
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