Number of the records: 1
talidomid
Record number d013792 Date 06.06.2025 Type M - MESH Topical term talidomid See also (Skutočné meno) imunosupresíva
(Skutočné meno) antileprotiká
(Skutočné meno) teratogény
(Skutočné meno) inhibítory angiogenézy
UDC D02.241.223.805.810.800D03.383.621.808.800D03.633.100.513.750.750 Note A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action. subject heading
Number of the records: 1