Number of the records: 1
cilastatín
SYS d015377 LBL 00000nz--a2200000o--4500 005 20250606214324.0 008 920603|||anznnbabn-----------|-a|a------ 040 $b slo $a DNLM $d BA006 065 $a D02.455.426.392.368.533.200 065 $a D10.251.355.325.200 066 $a 01 $c 03 150 $a cilastatín $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $2 slo 550 $7 sllk_us_auth*d011480 $Y Protease Inhibitors $w P $a inhibítory proteáz 665 $a 89 $2 eng 665 $a Cyclopropanes (1983-1988) $2 eng 665 $a Dipeptidases/antagonists & inhibitors (1983-1988) $2 eng 665 $a Protease Inhibitors (1983-1988) $2 eng 680 9-
$i A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4. $2 eng 750 -2
$a Cilastatin $2 eng 980 $x M
Number of the records: 1